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Kim S, Keku TO, Martin C, Galanko J, Woosley JT, Schroeder JC, et al

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Regression fits were performed separately for loci genome-wide significant for both mtCN raw and mtCN adj (black) and for loci specific to each (red)

Intracellular stores of Ca 2+ regulate cellular redox equilibrium by ROS formation and elimination, allowing cells to shift the redox environment towards either a more oxidizing or reducing state