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Approximately 70% to 90% of vitamin C is absorbed in moderate intakes of 30 to180 mg/day

The combination therapy was able to reduce infarct volume, preserve BBB integrity, attenuate microglia activation, decrease the required tPA dose, and improve neurological outcomes, even better than tPA alone [215, 216]

These myeloid immunosuppressive cells disrupt major mechanisms of immunosurveillance, including antigen presentation by dendritic cells, T-cell activation, and/or the cytotoxicity of NK cells