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The key factor affecting the switch from antioxidant to prooxidant properties of carotenoids has been attributed to the partial pressure of oxygen, typically high in the lungs

4 Systemic integration of exercise-induced stress responses The primary and secondary stress responses triggered by exercise ultimately converge at the systemic level, where hormones, myokines, neurotrophic factors, and immune mediators coordinate cross-tissue communication (81, 82)

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Inhibiting ROS production represents a viable strategy for mitigating mitochondrial damage

They found that inhalation of (+)-pinene in rats increased the duration of paradoxical sleep, also known as REMS through EEG and EMG recordings [39]