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Bei lteren Menschen funktionieren diese Stoffwechselvorgnge hufig nicht mehr zuverlssig

Subsequently, repair or degeneration occur, which depend on multiple factors such as the type and extent of damage, the immune system, the genetic susceptibility to disc degeneration, which is linked with age, the biomechanical (functional) condition that is created by the injury, and finally the type of treatment: conservative (disc loading) or operative (disc unloading)

10.1016/j.cmet.2016.09.010 Cell Metab

The extent and nature of -syns conformational changes directly correlate with PD progression and symptom severity (So and Watts 2023

35 ,36 The chemical structure of the polyphenols allows them to cross through the bloodbrain barrier, 3747 and its intake has been associated with neuronal protection against toxicant agents impact