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Convincing evidence indicates that n-3FA exert biological effects, in part, via the activation of PPAR receptors which regulate transcription of genes involved in cell proliferation, cell survival, apoptosis and cellular metabolism 24

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Despite low sequence conservation (2630% sequence identity, Supplementary Table S1), all of the UGT protein structures display the same secondary structure architecture (Supplementary Figs S2 and S3)