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Description

Benefits, where present, require continued administration nothing about the injection produces a lasting metabolic change once it stops

2017 doi: 10.1073/pnas.1703718114

However, resistance to the therapy later emerged, complicating treatment management

24 25 Some patients may experience recurrence or worsening of symptoms when the interval between injections is extended or extended too quickly, and report that continuation of frequent intramuscular hydroxocobalamin injections, varying between twice weekly and once every three to four weeks, 65 is needed to remain asymptomatic