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He started a course with his PT, which continued in parallel

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Reconstituted Vials After reconstitution, store vials refrigerated at 28C (3646F) and protected from light

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VacA insertion facilitates mitochondrial depolarization, swelling, and the release of pro-apoptotic factors such as apoptosis-inducing factor (AIF) and cytochrome c ( Listeria monocytogenes , an intracellular pathogen, secretes listeriolysin O (LLO), a cholesterol-dependent cytolysin that destabilizes host membranes, including mitochondrial membranes ( Staphylococcus aureus -toxin and phenol-soluble modulins perturb mitochondrial function, amplifying tissue destruction during severe infections such as pneumonia and sepsis ( 3.2 Bacterial manipulation of mitochondrial dynamics Mitochondrial fission and fusion processes, orchestrated by DRP1, MFN1/2, and OPA1, represent key checkpoints in cellular homeostasis